⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47241 | 1.00 | — | — | |
| SCHEMBL17203543 | 1.00 | — | — | |
| SCHEMBL9431600 | 1.00 | — | — | |
| SCHEMBL260640 | 1.00 | — | — | |
| Bromide SCHEMBL19834621 | 0.97 | CHRNA7 (0.94) | — | |
| Hydrochloric Acid SCHEMBL348634 | 0.97 | CHRNA7 (0.94) | — | |
| Hydrochloric Acid SCHEMBL260467 | 0.97 | CHRNA7 (0.94) | — | |
| Hydrochloric Acid SCHEMBL2183739 | 0.97 | CHRNA7 (0.94) | — | |
| Hydrochloric Acid SCHEMBL492194 | 0.97 | CHRNA7 (0.94) | — | |
| Bromide SCHEMBL7114503 | 0.97 | CHRNA7 (0.94) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531689-B | Acid addition salts of 3-aminoquinuclidine without deliquescence | 有机合成药品工业株式会社 | 2021-04-13 | — | — | CN | claimed |
| EP-3279199-B1 | NON-DELIQUESCENT ACID ADDITION SALT OF 3-AMINOQUINUCLIDINE | YUKI GOSEI YAKUHIN KOGYO KK (JP) | 2020-06-03 | — | — | EP | claimed |
| US-20180118736-A1 | NON-DELIQUESCENT ACID ADDITION SALT OF 3-AMINOQUINUCLIDINE | YUKI GOSEI KOGYO CO. LTD. (JP) | 2018-05-03 | — | — | US | claimed |
| EP-3279199-A1 | NON-DELIQUESCENT ACID ADDITION SALT OF 3-AMINOQUINUCLIDINE | YUKI GOSEI KOGYO CO., LTD. (JP) | 2018-02-07 | — | — | EP | claimed |
| WO-2017060287-A1 | PROCESS FOR THE PREPARATION OF ENCENICLINE FROM 7-CHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID CHLORIDE AND (R)-QUINUCLIDIN-3-AMINE IN THE PRESENCE OF IMIDAZOLE | SANDOZ AG (CH) | 2017-04-13 | — | — | WO | claimed |
| EP-2771340-B1 | 6-(4-HYDROXY-PHENYL)-1H-PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS | SANOFI SA (FR) | 2016-04-13 | — | — | EP | claimed |
| US-8178672-B2 | Synthesis of imidazooxazole and imidazothiazole inhibitors of p38 MAP kinase | ARQULE, INC. (US) | 2012-05-15 | — | — | US | claimed |
| EP-2258704-A1 | Synthesis of imidazooxazole and imidazothiazole inhibitors of p38 map kinase | ArQule, Inc. (US) | 2010-12-08 | — | — | EP | claimed |
| EP-1633752-B1 | ISOQUINOLINE-3-CARBOXYLIC ACID AMIDES AND PHARMACEUTICAL USES THEREOF | NOVARTIS AG (CH) | 2010-10-06 | — | — | EP | claimed |
| US-20090111985-A1 | Synthesis of imidazooxazole and imidazothiazole inhibitors of p38 map kinase | ARQULE, INC. | 2009-04-30 | — | — | US | claimed |
| EP-1809636-A1 | SYNTHESIS OF IMIDAZOOXAZOLE AND IMIDAZOTHIAZOLE INHIBITORS OF P38 MAP KINASE | ARQULE, INC. (US) | 2007-07-25 | — | — | EP | claimed |
| WO-2006044869-A1 | SYNTHESIS OF IMIDAZOOXAZOLE AND IMIDAZOTHIAZOLE INHIBITORS OF P38 MAP KINASE | ARQULE, INC. (US) | 2006-04-27 | — | — | WO | claimed |
| US-20050113574-A1 | Methods and compositions comprising diamines as new anti-tubercular therapeutics | SEQUELLA, INC. | 2005-05-26 | — | — | US | claimed |
| EP-0594569-A1 | PREPARATION OF S-(-)- AND R-(+)-N-(QUINUCLIDINYL-3)-AMIDE | CHIRON LABORATORIES A/S (NO) | 1994-05-04 | — | — | EP | claimed |
| US-5290938-A | Preparation of S-(-)- and R-(+)-N-(quinuclidinyl-3)-amide | CHIRON LABORATORIES A.S. (NO) | 1994-03-01 | — | — | US | claimed |
| WO-1991004253-A1 | PREPARATION OF S-(-)- AND R-(+)-N-(QUINUCLIDINYL-3)-AMIDE | CHIRON LABORATORIES A.S (NO) | 1991-04-04 | — | — | WO | claimed |
| EP-0311724-A1 | Anxiolytic-R-N-(1-azabicyclo[2.2.2]oct-3-yl) benzamides and thiobenzamides | SYNTHELABO (FR) | 1989-04-19 | — | — | EP | claimed |
| JP-1199969-A | — | — | None | — | — | JP | disclosed |
| EP-0312157-A2 | Tetrapeptide renin inhibitors having a novel c-terminal amino acid | MERCK & CO. INC. (US) | 1989-04-19 | — | — | EP | disclosed |
| EP-0311724-A1 | Anxiolytic-R-N-(1-azabicyclo[2.2.2]oct-3-yl) benzamides and thiobenzamides | SYNTHELABO (FR) | 1989-04-19 | — | — | EP | disclosed |