SCHEMBL427151

SCHEMBL427151

COC(=O)c1ccc(C(=O)OC)cc1.COC(=O)c1cccc(C(=O)OC)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.71
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
CA12 O43570 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA14 Q9ULX7 2/20 0.61
TDP1 Q9NUW8 1/20 0.61
LOXL2 Q9Y4K0 2/20 0.61
XDH P47989 1/20 0.61
CYP4F2 P78329 1/20 0.59
CYP4A11 Q02928 1/20 0.59
RAB9A P51151 4/20 0.58
POLB P06746 1/20 0.58
ALDH1A1 P00352 4/20 0.56
HPGD P15428 2/20 0.56
NPC1 O15118 2/20 0.56
MEN1 O00255 1/20 0.56
TP53 P04637 1/20 0.56
PKM P14618 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34953 0.95 TSHR (0.70) TSHRCA1CA2CA12CA7
Methyl Benzoate SCHEMBL28106657 0.93 TSHR (0.83) TSHRLOXL2CYP4F2CYP4A11RAB9A
Lithium SCHEMBL29634258 0.93 TSHR (0.67) TSHRCA1CA2CA12CA7
SCHEMBL10941453 0.93 TSHR (0.67) TSHRCA1CA2CA12CA7
Potassium SCHEMBL30190417 0.93 TSHR (0.67) TSHRCA1CA2CA12CA7
SCHEMBL9943503 0.93 TSHR (0.67) TSHRCA1CA2CA12CA7
Ammonia Solution, Strong SCHEMBL28556515 0.93 TSHR (0.67) TSHRCA1CA2CA12CA7
Methyl Alcohol SCHEMBL28469619 0.93 TSHR (0.67) TSHRCA1CA2CA12CA7
SCHEMBL8054504 0.93 TSHR (0.67) TSHRCA1CA2CA12CA7
SCHEMBL29966404 0.93 TSHR (0.67) TSHRCA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11369498-B2 Stent and stent delivery system with improved deliverability MT Acquisition Holdings LLC (US) 2022-06-28 US disclosed
US-10675449-B2 High pressure balloon BOSTON SCIENTIFIC SCIMED, INC. (US) 2020-06-09 US disclosed
CN-110168026-A Coating composition PPG工业俄亥俄公司 2019-08-23 CN disclosed
US-20190030301-A1 HIGH PRESSURE BALLOON BOSTON SCIENTIFIC SCIMED, INC. (US) 2019-01-31 US disclosed
US-10099039-B2 High pressure balloon BOSTON SCIENTIFIC SCIMED, INC. (US) 2018-10-16 US disclosed
CN-104955911-B Coating composition PPG工业俄亥俄公司 2018-06-05 CN disclosed
EP-2531140-B1 STENT AND STENT DELIVERY SYSTEM WITH IMPROVED DELIVERABILITY MICELL TECHNOLOGIES INC (US) 2017-11-01 EP disclosed
US-20170065795-A1 HIGH PRESSURE BALLOON BOSTON SCIENTIFIC SCIMED, INC. (US) 2017-03-09 US disclosed
US-9586030-B2 Fugitive plasticizer balloon surface treatment for enhanced stent securement BOSTON SCIENTIFIC SCIMED, INC. (US) 2017-03-07 US disclosed
US-9526873-B2 High pressure balloon BOSTON SCIENTIFIC SCIMED, INC. (US) 2016-12-27 US disclosed
WO-2006016934-A1 HIGH PERFORMANCE BALLOON CATHETER/COMPONENT BOSTON SCIENTIFIC LIMITED (BB) 2006-02-16 WO disclosed
US-20060008606-A1 High performance balloon catheter/component SCIMED LIFE SYSTEMS, INC. (US) 2006-01-12 US disclosed
US-20050146085-A1 Process and apparatus for forming medical device balloons SCIMED LIFE SYSTEMS, INC. (US) 2005-07-07 US disclosed
EP-0554728-B1 Mixtures that are storage-stable at room temperature and their use as binders in coating compositions BAYER AG (DE) 1996-02-14 EP disclosed
CN-1111452-A Polyol for producing polyurethane foams, polyurethane foams and production thereof DOW CHEMICAL CO (US) 1995-11-08 CN disclosed
US-5330428-A Copolyester SCIMED LIFE SYSTEMS, INC. (US) 1994-07-19 US disclosed
US-5330428-A Copolyester SCIMED LIFE SYSTEMS, INC. (US) 1994-07-19 US disclosed
US-4119608-A MONOETHER OF DIETHYLENE GLYCOL OR TRIETHYLENE GLYCOL SCHENECTADY CHEMICALS, INC. (US) 1978-10-10 US disclosed
US-4119605-A MONOETHER OF DIETHYLENE GLYCOL OR TRIETHYLENE GLYCOL SCHENECTADY CHEMICALS, INC. (US) 1978-10-10 US disclosed
US-4119758-A Electrical conductors having insulating coatings from solutions of polyester-imides SCHENECTADY CHEMICALS, INC. (US) 1978-10-10 US disclosed