Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26391489 | 1.00 | TSHR (0.52) | TSHRLMNAL3MBTL1ALDH1A1TP53 | |
| SCHEMBL304806 | 1.00 | TSHR (0.52) | TSHRLMNAL3MBTL1ALDH1A1TP53 | |
| SCHEMBL1160693 | 1.00 | TSHR (0.52) | TSHRLMNAL3MBTL1ALDH1A1TP53 | |
| SCHEMBL12019522 | 0.98 | TSHR (0.50) | TSHRLMNAL3MBTL1ALDH1A1TP53 | |
| SCHEMBL28121242 | 0.98 | TSHR (0.50) | TSHRLMNAL3MBTL1ALDH1A1TP53 | |
| SCHEMBL307713 | 0.96 | TSHR (0.52) | TSHRLMNAL3MBTL1ALDH1A1TP53 | |
| SCHEMBL2476532 | 0.96 | TSHR (0.52) | TSHRLMNAL3MBTL1ALDH1A1TP53 | |
| SCHEMBL13997350 | 0.92 | TSHR (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL14005956 | 0.92 | TSHR (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL12019523 | 0.90 | TSHR (0.57) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090294362-A1 | STATIONARY PHASE FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2009-12-03 | — | — | US | claimed |
| US-20090294362-A1 | STATIONARY PHASE FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2009-12-03 | — | — | US | disclosed |
| US-4241131-A | Moldable polyurethane foam-backed fabrics | MOBAY CHEMICAL CORPORATION (US) | 1980-12-23 | — | — | US | disclosed |