Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267885 | 0.89 | PTGDR2 (0.41) | PTGDR2PTGDR | |
| SCHEMBL4276035 | 0.89 | PTGDR2 (0.41) | PTGDR2PTGDR | |
| SCHEMBL4272479 | 0.82 | PTGDR2 (0.48) | PTGDR2PTGDRDHFR | |
| SCHEMBL4272358 | 0.79 | PTGDR2 (0.57) | PTGDR2PTGDRLTB4R | |
| SCHEMBL4272320 | 0.78 | PTGDR2 (0.56) | PTGDR2PTGDR | |
| SCHEMBL4271985 | 0.78 | PTGDR2 (0.56) | PTGDR2PTGDR | |
| SCHEMBL4275920 | 0.76 | PTGDR2 (0.45) | PTGDR2PTGDRALDH1A1DHFR | |
| SCHEMBL4276046 | 0.75 | PTGDR2 (0.41) | PTGDR2PTGDR | |
| SCHEMBL4267501 | 0.74 | PTGDR2 (0.55) | PTGDR2PTGDRALDH1A1 | |
| SCHEMBL4271717 | 0.73 | PTGDR2 (0.41) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094662-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008072784-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2008-06-19 | — | — | WO | disclosed |