Sugi Predict

Sugi Predict / Compounds / Tryptophan

Tryptophan

Tryptophan

SCHEMBL4274128

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.O=C1NC(=S)NC1c1ccccc1

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.65
▸ MAPT P10636 4/20 0.65
▸ KDM4E B2RXH2 3/20 0.65
▸ MEN1 O00255 3/20 0.65
▸ LMNA P02545 2/20 0.65
▸ TSHR P16473 2/20 0.65
▸ BLM P54132 2/20 0.65
▸ PMP22 Q01453 2/20 0.65
▸ MPO P05164 1/20 0.65
▸ HIF1A Q16665 1/20 0.65
▸ IDO1 P14902 1/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ HTR1A P08908 1/20 0.47
▸ ADORA3 P0DMS8 1/20 0.47
▸ ALOX15 P16050 1/20 0.47
▸ NFKB1 P19838 1/20 0.47
▸ HTR2A P28223 1/20 0.47
▸ HTR2C P28335 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophan SCHEMBL1764941 0.87 KMT2A (0.67) KMT2AMAPTKDM4EMEN1LMNA
Dl-Tryptophan SCHEMBL289042 0.81 KMT2A (1.00) KMT2AMAPTKDM4EMEN1LMNA
Dl-Tryptophan SCHEMBL7327 0.81 KMT2A (1.00) KMT2AMAPTKDM4EMEN1LMNA
Dl-Tryptophan SCHEMBL1120026 0.81 KMT2A (1.00) KMT2AMAPTKDM4EMEN1LMNA
Dl-Tryptophan SCHEMBL475349 0.81 KMT2A (1.00) KMT2AMAPTKDM4EMEN1LMNA
Tryptophan SCHEMBL23141133 0.81 KMT2A (1.00) KMT2AMAPTKDM4EMEN1LMNA
Dl-Tryptophan SCHEMBL4732052 0.81 KMT2A (1.00) KMT2AMAPTKDM4EMEN1LMNA
Tryptophan SCHEMBL4732053 0.81 KMT2A (1.00) KMT2AMAPTKDM4EMEN1LMNA
Dl-Tryptophan SCHEMBL19161120 0.81 KMT2A (1.00) KMT2AMAPTKDM4EMEN1LMNA
Tryptophan SCHEMBL475350 0.81 KMT2A (1.00) KMT2AMAPTKDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0447746-A1 A method for separating Diphenylurea(DPU) and phenylthiohydantoin-tryptophan (PTH-TRP) allowing unambiguous indentification of TRP in automatic sequence analysis AMERICAN CYANAMID COMPANY (US) 1991-09-25 — — EP claimed
CN-101937778-B Dye sensitization photoelectric converter SONY CORP 2013-05-01 — — CN disclosed
US-8415558-B2 Dye sensitization photoelectric converter SONY CORPORATION (JP) 2013-04-09 — — US disclosed
CN-101416345-B Dye-sensitized photoelectric conversion device SONY CORP 2012-09-26 — — CN disclosed
CN-101937778-A Dye sensitization photoelectric converter SONY CORP 2011-01-05 — — CN disclosed
US-20090217979-A1 Dye Sensitization Photoelectric Converter SONY CORPORATION (JP) 2009-09-03 — — US disclosed
CN-101416345-A Dye-sensitized photoelectric conversion device SONY CORP (JP) 2009-04-22 — — CN disclosed
EP-1981118-A1 DYE SENSITIZATION PHOTOELECTRIC CONVERTER Sony Corporation (JP) 2008-10-15 — — EP disclosed
US-5143851-A METHOD FOR SEPARATING DIPHENYLUREA (DPU) AND PHENYLTHIOHYDANTOIN-TRYPTOPHAN (PTH-TRP) ALLOWING UNAMBIGUOUS IDENTIFICATION OF TRP IN AUTOMATIC SEQUENCE ANALYSIS AMERICAN CYANAMID COMPANY (US) 1992-09-01 — — US disclosed
EP-0447746-A1 A method for separating Diphenylurea(DPU) and phenylthiohydantoin-tryptophan (PTH-TRP) allowing unambiguous indentification of TRP in automatic sequence analysis AMERICAN CYANAMID COMPANY (US) 1991-09-25 — — EP disclosed
EP-0447746-A1 A method for separating Diphenylurea(DPU) and phenylthiohydantoin-tryptophan (PTH-TRP) allowing unambiguous indentification of TRP in automatic sequence analysis AMERICAN CYANAMID COMPANY (US) 1991-09-25 — — EP disclosed