Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 9/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252422 | 0.93 | PTGDR2 (0.72) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL2549980 | 0.93 | PTGDR2 (0.72) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1251040 | 0.92 | PTGDR2 (0.54) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1251019 | 0.84 | PTGDR2 (0.68) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL5731063 | 0.82 | PTGDR2 (0.43) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL4274593 | 0.82 | PTGDR2 (0.56) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1251026 | 0.80 | PTGDR2 (0.68) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL12913905 | 0.80 | PTGDR2 (0.59) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL5732122 | 0.80 | PTGDR2 (0.54) | PTGDR2AKR1B1CYP2C9 | |
| SCHEMBL1252380 | 0.79 | PTGDR2 (0.69) | PTGDR2AKR1B1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025670-A1 | 3-(Phenyl or quinolyl)thio-1H-indole-1-acetic acid derivatives as modulators of CRTh2 receptor activity | AstraZeneca AB (SE) | 2009-02-18 | — | — | EP | disclosed |