SCHEMBL4274674

SCHEMBL4274674

O=[C]C(I)I

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6989006 0.70
Carbon Dioxide SCHEMBL318318 0.60
Iodoform SCHEMBL28703104 0.60
SCHEMBL1006909 0.56
SCHEMBL2863302 0.56
SCHEMBL16150499 0.56
SCHEMBL2995 0.56
SCHEMBL652953 0.56
SCHEMBL620413 0.56
SCHEMBL179140 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3962253-A OXIDATION OF SELECTIVELY PROTECTED 2,3-DIHYDRO-6-METHYL-8-HYDROXY-9-ERGOLENES ELI LILLY AND COMPANY (US) 1976-06-08 US claimed
WO-2024020780-A1 STAR-SHAPED POLYMER, PAINT, COATING, AND METHOD FOR PRODUCING STAR-SHAPED POLYMER DIC CORPORATION (JP) 2024-02-01 WO disclosed
CN-114728992-A Method for producing phosphate compound 斯泰拉化工公司 2022-07-08 CN disclosed
US-20130217037-A1 FUNCTIONALIZATION OF GOLD NANOPARTICLES WITH ORIENTED PROTEINS, APPLICATION TO THE HIGH-DENSITY LABELING OF CELL MEMBRANES BRISSON ALAIN (FR) 2013-08-22 US disclosed
US-20090098574-A1 FUNCTIONALIZATION OF GOLD NANOPARTICLES WITH ORIENTED PROTEINS, APPLICATION TO THE HIGH-DENSITY LABELLING OF CELL MEMBRANES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) 2009-04-16 US disclosed
EP-2018559-A1 FUNCTIONALIZATION OF GOLD NANOPARTICLES WITH ORIENTED PROTEINS. APPLICATION TO THE HIGH-DENSITY LABELLING OF CELL MEMBRANES Centre National de la Recherche Scientifique (CNRS) (FR) 2009-01-28 EP disclosed
WO-2007122259-A1 FUNCTIONALIZATION OF GOLD NANOPARTICLES WITH ORIENTED PROTEINS. APPLICATION TO THE HIGH-DENSITY LABELLING OF CELL MEMBRANES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2007-11-01 WO disclosed
US-5273998-A Process for making an optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compound YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1993-12-28 US disclosed
US-5177216-A DIASTEREOMERIC ESTER COMPOUND USEFUL AS AN INTERMEDIATE IN THE MAKING OF AN OPTICALLY ACTIVE 3,4-DIHYDRO-3,4-EPOXY-2H-1-BENZOPYRAN COMPOUND YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1993-01-05 US disclosed
US-5162553-A Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds and intermediates therefor YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1992-11-10 US disclosed
US-5066816-A PROCESSES FOR PREPARING OPTICALLY ACTIVE 3,4-DIHYDRO-3,4-EPOXY-2H-1-BENZOPYRAN COMPOUNDS AND INTERMEDIATES THEREFOR YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1991-11-19 US disclosed
EP-0456266-A1 Method for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds, intermediates therefor and uses thereof YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1991-11-13 EP disclosed
EP-0386640-A2 Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds and intermediates therefor YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1990-09-12 EP disclosed
US-4757138-A Reacting 4'-halogenoacetal-4'-demethylepipodophyllotoxin-beta-D-2,3-di-o -halogenoacetyl-4,6-o-ethylidene glucoside with lower alcohols in the presence of an organic carboxylic acid ammonium salt NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1988-07-12 US disclosed
EP-0162701-A2 Process for producing etoposide and intermediate for use therein NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1985-11-27 EP disclosed
US-4472386-A 5-Fluoro-(β-uridine or 2'-deoxy-β-uridine) derivatives, a process for producing the same and a carcinostatic agent containing the same TOYAMA CHEMICAL CO., LTD. (JP) 1984-09-18 US disclosed
US-3962253-A OXIDATION OF SELECTIVELY PROTECTED 2,3-DIHYDRO-6-METHYL-8-HYDROXY-9-ERGOLENES ELI LILLY AND COMPANY (US) 1976-06-08 US disclosed
US-3940441-A BACTERICIDE STERLING DRUG INC. (US) 1976-02-24 US disclosed