SCHEMBL4275745

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL34465316	1.00	SMN1; SMN2 (0.41)	SMN1; SMN2POLBFPR2KDM4ELMNA
	SCHEMBL4279400	1.00	SMN1; SMN2 (0.41)	SMN1; SMN2POLBFPR2KDM4ELMNA
	SCHEMBL4280692	0.96	SMN1; SMN2 (0.41)	SMN1; SMN2POLBKDM4ELMNAHSD17B10
	SCHEMBL4276621	0.95	KDM4E (0.41)	KDM4ELMNAHSD17B10MAPTHPGD
	SCHEMBL13701425	0.95	LCLAT1 (0.40)	SMN1; SMN2FPR2KDM4ELMNAHSD17B10
	SCHEMBL4280633	0.95	SMN1; SMN2 (0.45)	SMN1; SMN2POLBKDM4ELMNAHSD17B10
	SCHEMBL4280889	0.94	S1PR1 (0.42)	SMN1; SMN2POLBFPR2KDM4ELMNA
	SCHEMBL13701424	0.94	SMN1; SMN2 (0.45)	SMN1; SMN2POLBKDM4ELMNAHSD17B10
	SCHEMBL4270743	0.94	SMN1; SMN2 (0.45)	SMN1; SMN2POLBKDM4ELMNAHSD17B10
	SCHEMBL4269891	0.92	POLB (0.46)	SMN1; SMN2POLBNPSR1PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.