Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 17/20 | 0.64 |
| ▸ | CTSD | P07339 | 14/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4276050 | 1.00 | BACE1 (0.64) | BACE1CTSDOPRK1 | |
| SCHEMBL3501218 | 0.90 | BACE1 (0.77) | BACE1CTSD | |
| SCHEMBL4262344 | 0.90 | BACE1 (0.66) | BACE1CTSDOPRK1 | |
| SCHEMBL4262339 | 0.90 | BACE1 (0.66) | BACE1CTSDOPRK1 | |
| SCHEMBL3501217 | 0.90 | BACE1 (0.77) | BACE1CTSD | |
| SCHEMBL3501219 | 0.90 | BACE1 (0.77) | BACE1CTSD | |
| SCHEMBL5714111 | 0.90 | BACE1 (0.77) | BACE1CTSD | |
| SCHEMBL6508809 | 0.88 | BACE1 (0.50) | BACE1CTSD | |
| SCHEMBL8282473 | 0.86 | BACE1 (0.65) | BACE1CTSDOPRK1 | |
| SCHEMBL4264996 | 0.85 | BACE1 (0.70) | BACE1CTSDOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544717-B2 | 2-amino- and 2-thio- substituted 1,3-diaminopropanes | ELAN PHARMACEUTICALS, INC. (US) | 2009-06-09 | — | — | US | claimed |
| US-7544717-B2 | 2-amino- and 2-thio- substituted 1,3-diaminopropanes | ELAN PHARMACEUTICALS, INC. (US) | 2009-06-09 | — | — | US | disclosed |
| US-20050267199-A1 | 2-Amino- and 2-thio- substituted 1,3-diaminopropanes | ELAN PHARMACEUTICALS, INC. | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267199-A1 | 2-Amino- and 2-thio- substituted 1,3-diaminopropanes | BACE1, APP, BACE2 | BACE1 1/4885CTSD 311/4885OPRK1 2906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.