SCHEMBL4276134

SCHEMBL4276134

NC1(C(=O)O)C=CC=CC1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrolidine SCHEMBL28363734 0.87
Benzene SCHEMBL28845726 0.84
SCHEMBL364687 0.84
SCHEMBL31304107 0.82
SCHEMBL6358962 0.80
SCHEMBL6032163 0.80
SCHEMBL10839446 0.78 CRBN (0.47)
SCHEMBL10840979 0.77 HDAC6 (0.36)
SCHEMBL8665715 0.77
SCHEMBL10838386 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10888839-B2 Average-density-adjustable structure, and material change and selective bonding process using same KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2021-01-12 US disclosed
US-20180185818-A1 AVERAGE-DENSITY-ADJUSTABLE STRUCTURE, AND MATERIAL CHANGE AND SELECTIVE BONDING PROCESS USING SAME KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2018-07-05 US disclosed
US-20090088339-A1 IDENTIFICATION OF ACTIVATED RECEPTORS AND ION CHANNELS THE JOHNS HOPKINS UNIVERSITY 2009-04-02 US disclosed
US-7462457-B2 Identification of activated receptors and ion channels JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) 2008-12-09 US disclosed
US-7393318-B2 Methods and compositions for interaction trap assays MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-07-01 US disclosed
US-7297491-B2 Methods and compositions for interaction trap assays MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-11-20 US disclosed
US-20060205017-A1 Microorganism genomics, compositions and methods related thereto HANDELSMAN JO 2006-09-14 US disclosed
EP-1379642-A4 ARRAYED TRANSFECTION METHOD AND USES RELATED THERETO WHITEHEAD BIOMEDICAL INST (US) 2006-04-19 EP disclosed
US-7029847-B2 Detection dimerizing test polypeptide; obtain population of genetically engineered cells, express vector, isolate cells expressing desired concentration of reporter molecule MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2006-04-18 US disclosed
US-7008767-B2 Microorganism genomics, compositions and methods related thereto WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2006-03-07 US disclosed
WO-1998013513-A2 METHODS AND COMPOSITIONS FOR IDENTIFYING RECEPTOR EFFECTORS CADUS PHARMACEUTICAL CORPORATION (US) 1998-04-02 WO disclosed
WO-1998012339-A2 VIRAL VECTORS AND THEIR USES COLD SPRING HARBOR LABORATORY (US) 1998-03-26 WO disclosed
EP-0815081-A1 PIPERIDINYL-2-ALKYL SUBST. LINEAR POLYAMINES FOR THE REDUCTION OF INTRACELLULAR, ENDOGENIC POLYAMINE LEVELS SUCH AS PUTRESCINE, SPERMIDINE AND SPERMINE, AND THEIR IMPACT ON CELL PROLIFERATION Novartis AG (CH) 1998-01-07 EP disclosed
WO-1997049557-A1 LITHOGRAPHIC PLATES HORSELL GRAPHIC INDUSTRIES LIMITED (GB) 1997-12-31 WO disclosed
US-5627215-A Unsaturate amino compounds for use as anticancer and antiprotozoic agent CIBA-GEIGY CORPORATION (US) 1997-05-06 US disclosed
WO-1996028425-A1 PIPERIDINYL-2-ALKYL SUBST. LINEAR POLYAMINES FOR THE REDUCTION OF INTRACELLULAR, ENDOGENIC POLYAMINE LEVELS SUCH AS PUTRESCINE, SPERMIDINE AND SPERMINE, AND THEIR IMPACT ON CELL PROLIFERATION NOVARTIS AG (CH) 1996-09-19 WO disclosed
US-5527681-A Immobilized molecular synthesis of systematically substituted compounds AFFYMAX TECHNOLOGIES N.V. (NL) 1996-06-18 US disclosed
EP-0686143-A1 UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT Novartis AG (CH) 1995-12-13 EP disclosed
WO-1995018091-A1 UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT CIBA-GEIGY AG (CH) 1995-07-06 WO disclosed
US-5424186-A Biosynthesis of oligonucleotides on solid substrate by irradiation of predefined segments to remove blocking agents; then coupling with nucleotide AFFYMAX TECHNOLOGIES N.V. (AN) 1995-06-13 US disclosed