Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5404513 | 0.90 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8520341 | 0.87 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| Ethylenediamine SCHEMBL10929030 | 0.86 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31016723 | 0.85 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28334588 | 0.85 | TSHR (0.36) | TSHRTHRBALDH1A1 | |
| SCHEMBL27874553 | 0.85 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4349070 | 0.85 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL25812321 | 0.84 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14122934 | 0.82 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL192216 | 0.82 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043356-B1 | Low modulus, one part RTV sealant compositions | MOMENTIVE PERFORMANCE MAT INC (US) | 2009-12-09 | — | — | EP | disclosed |