SCHEMBL4277002

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4273056	0.97	PDE4D (0.40)	PDE4DPDE4BPDE4APDE4CPDE5A
	SCHEMBL4271309	0.91	PDE4B (0.38)	PDE4DPDE4BPDE4APDE4C
	SCHEMBL4286025	0.90	PDE4B (0.40)	PDE4DPDE4BPDE4APDE4C
	SCHEMBL4281548	0.90	PDE4A (0.37)	PDE4DPDE4BPDE4APDE4C
	SCHEMBL4270571	0.88	PDE4B (0.38)	PDE4DPDE4BPDE4APDE4C
	SCHEMBL4277707	0.88	S1PR1 (0.37)	PDE4DPDE4BPDE4APDE4C
	SCHEMBL4271374	0.88	S1PR1 (0.37)	PDE4DPDE4BPDE4APDE4C
	SCHEMBL4274963	0.87	PDE4B (0.42)	PDE4DPDE4BPDE4APDE4C
	SCHEMBL4274938	0.87	PDE4B (0.40)	PDE4DPDE4BPDE4APDE4C
	SCHEMBL4276856	0.87	PDE4B (0.35)	PDE4DPDE4BPDE4APDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.