SCHEMBL4278570

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4272595	0.97	KDM4E (0.37)	KDM4EPPARGPPARALCLAT1ALDH1A1
	SCHEMBL4276715	0.92	LCLAT1 (0.35)	KDM4EPPARGPPARALCLAT1ALDH1A1
	SCHEMBL4281537	0.92	LCLAT1 (0.39)	KDM4EPPARGPPARALCLAT1ALDH1A1
	SCHEMBL4275143	0.90	PDE4A (0.40)	KDM4EPPARGPPARALCLAT1ALDH1A1
	SCHEMBL4284521	0.89	PARP1 (0.36)	KDM4ELCLAT1ALDH1A1SMN1; SMN2S1PR1
	SCHEMBL4280239	0.89	KDM4E (0.41)	KDM4EPPARGPPARAALDH1A1SMN1; SMN2
	SCHEMBL4283091	0.89	LCLAT1 (0.39)	KDM4EPPARGPPARALCLAT1ALDH1A1
	SCHEMBL4274922	0.88	SMN1; SMN2 (0.38)	KDM4ELCLAT1SMN1; SMN2S1PR1HSD17B10
	SCHEMBL4280844	0.87	PDE4A (0.38)	KDM4EPPARGPPARALCLAT1ALDH1A1
	SCHEMBL4274769	0.86	SMN1; SMN2 (0.39)	KDM4EALDH1A1SMN1; SMN2S1PR1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.