Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4390251 | 1.00 | MTOR (0.82) | MTORPIK3CA | |
| SCHEMBL4280382 | 1.00 | MTOR (0.82) | MTORPIK3CA | |
| SCHEMBL4390421 | 0.92 | MTOR (0.87) | MTORPIK3CA | |
| SCHEMBL4390423 | 0.92 | MTOR (0.87) | MTORPIK3CA | |
| SCHEMBL4288312 | 0.91 | MTOR (0.85) | MTORPIK3CA | |
| SCHEMBL4383560 | 0.91 | MTOR (0.85) | MTORPIK3CA | |
| SCHEMBL4284596 | 0.91 | MTOR (0.84) | MTORPIK3CA | |
| SCHEMBL4379987 | 0.91 | MTOR (0.84) | MTORPIK3CA | |
| SCHEMBL4380269 | 0.91 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL4282072 | 0.91 | MTOR (1.00) | MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155052-A1 | 3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH (US) | 2009-12-23 | — | — | WO | claimed |
| WO-2009155052-A1 | 3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH (US) | 2009-12-23 | — | — | WO | disclosed |