SCHEMBL4280381

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4271318	0.93	DHODH (0.46)	DHODHPDE4BMAPTABCB1CTNNB1
	SCHEMBL4284260	0.92	DHODH (0.43)	DHODHPDE4BMAPTABCB1CTNNB1
	SCHEMBL4271720	0.92	DHODH (0.44)	DHODHPDE4BMAPTABCB1CTNNB1
	SCHEMBL4284459	0.91	S1PR1 (0.37)	DHODHPDE4BPDE4APDE4CPDE4D
	SCHEMBL4280889	0.91	S1PR1 (0.42)	PDE4BPDE4APDE4CPDE4DMAPT
	SCHEMBL4282877	0.89	LCLAT1 (0.41)	DHODHKCNH2ABCB1CTNNB1WNT3A
	SCHEMBL4279411	0.88	PDE4A (0.42)	PDE4BPDE4APDE4CPDE4DMAPT
	SCHEMBL4271812	0.88	KDM4E (0.41)	PDE4BPDE4APDE4CPDE4DCTNNB1
	SCHEMBL4275157	0.88	LCLAT1 (0.38)	PDE4BPDE4APDE4CPDE4DKCNH2
	SCHEMBL4279520	0.87	CTNNB1 (0.38)	MAPTABCB1CTNNB1WNT3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.