SCHEMBL4280402

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL34465347	1.00	PDE4B (0.39)	PDE4BPDE4APDE4DPDE4CIRAK4
	SCHEMBL4272532	0.97	IRAK4 (0.40)	PDE4BPDE4APDE4DPDE4CIRAK4
	SCHEMBL4284472	0.93	PDE4B (0.42)	PDE4BPDE4APDE4DPDE4CFPR2
	SCHEMBL29813509	0.90	PDE4B (0.40)	PDE4BPDE4APDE4DPDE4CFPR2
	SCHEMBL4275689	0.90	PDE4B (0.40)	PDE4BPDE4APDE4DPDE4CFPR2
	SCHEMBL4273489	0.90	S1PR1 (0.41)	PDE4BPDE4APDE4DPDE4CIRAK4
	SCHEMBL13701426	0.90	S1PR1 (0.43)	IRAK4S1PR1S1PR3S1PR5MAPT
	SCHEMBL4278967	0.89	SMN1; SMN2 (0.41)	IRAK4S1PR1S1PR3S1PR5LMNA
	SCHEMBL4276113	0.89	PDE4B (0.39)	PDE4BPDE4APDE4DPDE4CFPR2
	SCHEMBL4273527	0.89	PDE4B (0.43)	PDE4BPDE4APDE4DPDE4CFPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.