SCHEMBL4280677

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6944861	0.95	MAPK1 (1.00)	MAPK1TSHRPDE4APDE4BPDE4C
	SCHEMBL1402177	0.93	MAPK1 (0.84)	MAPK1TSHRPDE4APDE4BPDE4C
	SCHEMBL28332599	0.88	MAPK1 (0.71)	MAPK1TSHRPDE4APDE4BPDE4C
	SCHEMBL4826029	0.88	TSHR (0.72)	MAPK1TSHRPDE4APDE4BPDE4C
	SCHEMBL5076592	0.86	TSHR (0.76)	MAPK1TSHRPDE4APDE4BPDE4C
	SCHEMBL3612256	0.86	TSHR (0.87)	MAPK1TSHRPDE4APDE4BPDE4C
	SCHEMBL1824358	0.86	MAPK1 (0.69)	MAPK1TSHRPDE4APDE4BPDE4C
	SCHEMBL15521570	0.85	MAPK1 (0.68)	MAPK1PDE4APDE4BPDE4CPDE4D
	SCHEMBL335681	0.85	MAPK1 (0.77)	MAPK1TSHRPARP10L3MBTL1CYP1A2
	SCHEMBL29415167	0.85	MAPK1 (0.77)	MAPK1TSHRPARP10L3MBTL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.