SCHEMBL4281137

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4280644	0.96	KDM4E (0.41)	LCLAT1ALDH1A1HPGDMAPTHTT
	SCHEMBL4280844	0.94	PDE4A (0.38)	LCLAT1ALDH1A1HPGDMAPTHTT
	SCHEMBL4278967	0.94	SMN1; SMN2 (0.41)	ALDH1A1HPGDMAPTS1PR1KDM4E
	SCHEMBL4271153	0.94	SMN1; SMN2 (0.39)	LCLAT1ALDH1A1HPGDMAPTHTT
	SCHEMBL4280787	0.92	KDM4E (0.45)	LCLAT1ALDH1A1HPGDMAPTHTT
	SCHEMBL4283091	0.92	LCLAT1 (0.39)	LCLAT1ALDH1A1HPGDMAPTHTT
	SCHEMBL4275143	0.90	PDE4A (0.40)	LCLAT1ALDH1A1HPGDMAPTHTT
	SCHEMBL4280633	0.90	SMN1; SMN2 (0.45)	LCLAT1ALDH1A1HPGDMAPTS1PR1
	SCHEMBL4281537	0.88	LCLAT1 (0.39)	LCLAT1ALDH1A1HPGDMAPTHTT
	SCHEMBL4276621	0.88	KDM4E (0.41)	LCLAT1ALDH1A1HPGDMAPTS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.