SCHEMBL4281241

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4284392	0.93	LCLAT1 (0.38)	LCLAT1SMN1; SMN2ABCB1MAPTALDH1A1
	SCHEMBL4283091	0.93	LCLAT1 (0.39)	LCLAT1SMN1; SMN2ABCB1MAPTALDH1A1
	SCHEMBL4275143	0.93	PDE4A (0.40)	LCLAT1SMN1; SMN2ABCB1MAPTALDH1A1
	SCHEMBL4281537	0.93	LCLAT1 (0.39)	LCLAT1SMN1; SMN2ABCB1MAPTALDH1A1
	SCHEMBL4274922	0.90	SMN1; SMN2 (0.38)	LCLAT1SMN1; SMN2MAPTHPGDMEN1
	SCHEMBL4280844	0.90	PDE4A (0.38)	LCLAT1SMN1; SMN2ABCB1MAPTALDH1A1
	SCHEMBL4276073	0.89	GAA (0.38)	LCLAT1ABCB1MAPTALDH1A1HPGD
	SCHEMBL4271880	0.89	TSHR (0.41)	LCLAT1SMN1; SMN2ABCB1MAPTALDH1A1
	SCHEMBL4285247	0.89	SMN1; SMN2 (0.40)	LCLAT1SMN1; SMN2MAPTALDH1A1HPGD
	SCHEMBL4280745	0.88	PDE4A (0.40)	ABCB1TSHRPPARGPPARAPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.