SCHEMBL428169

SCHEMBL428169

O=Cc1c(O)cccc1S(=O)(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.43
AURKB Q96GD4 1/20 0.43
CDK2 P24941 1/20 0.42
ERN1 O75460 5/20 0.42
STAT3 P40763 1/20 0.42
TTR P02766 2/20 0.41
TRIM24 O15164 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
MAOA P21397 2/20 0.39
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
MAOB P27338 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3294201 0.87 TTR (0.47) AURKAAURKBCDK2ERN1TTR
SCHEMBL9780321 0.87 ERN1 (0.56) AURKAAURKBCDK2ERN1TTR
SCHEMBL28375176 0.85 TTR (0.45) AURKAAURKBCDK2ERN1TTR
SCHEMBL17982110 0.85 TTR (0.45) AURKAAURKBCDK2TTRALDH1A1
SCHEMBL8336771 0.82 AURKA (0.42) AURKAAURKBCDK2STAT3TTR
SCHEMBL8133371 0.80 DUSP5 (0.46) CDK2ERN1STAT3TTRTRIM24
SCHEMBL311198 0.79 ERN1 (0.54) CDK2ERN1TTRTRIM24TRIM33
SCHEMBL28565466 0.79 TDP1 (0.42) CDK2ERN1TTRTRIM24TRIM33
SCHEMBL24801172 0.78 ERN1 (0.42) ERN1TTRALDH1A1TDP1MEN1
SCHEMBL14388231 0.78 MYC (0.42) CDK2TTRTRIM24TRIM33ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0632096-B1 Redispersible dispersion powder composition WACKER CHEMIE GMBH (DE) 1995-12-20 EP claimed
EP-2282633-B1 METHOD FOR MANUFACTURING PARTICLES CONTAINING AGRO-CHEMICAL INGREDIENTS IN AN AMORPHOUS FORM BASF SE (DE) 2019-03-13 EP disclosed
US-9265250-B2 Liquid active ingredient concentrates that can be emulsified in water BASF SE (DE) 2016-02-23 US disclosed
US-8957133-B2 Polyamide moldings comprising microencapsulated latent-heat-accumulator material BASF SE (DE) 2015-02-17 US disclosed
CN-102014617-B Emulsifiable concentrate BASF SE (DE) 2014-10-01 CN disclosed
US-8491992-B2 Laminar component made from composite material BASF SE (DE) 2013-07-23 US disclosed
US-20130046103-A1 PREPARATION OF BENZOFURANS AND USE THEREOF AS SYNTHETIC INTERMEDIATES MAPI PHARMA LIMITED (IL) 2013-02-21 US disclosed
EP-2533636-A1 PREPARATION OF BENZOFURANS AND USE THEREOF AS SYNTHETIC INTERMEDIATES Mapi Pharma Limited (IL) 2012-12-19 EP disclosed
EP-2528959-A1 METHOD FOR PRODUCING PHENOLSULFONIC ACID ALDEHYDE CONDENSATION PRODUCTS AND THE USE THEREOF AS DESICCANTS BASF SE (DE) 2012-12-05 EP disclosed
US-20120022187-A1 POLYAMIDE MOLDINGS COMPRISING MICROENCAPSULATED LATENT-HEAT-ACCUMULATOR MATERIAL BASF SE (DE) 2012-01-26 US disclosed
CN-1078599-C Re-dispersible polymer powder and aqueous polymer dispersions obtained from it WACKER CHEMIE GMBH (DE) 2002-01-30 CN disclosed
US-6242512-B1 DRYING WATER INSOLUBLE POLYMER, WATER SOLUBLE PROTECTIVE COLLOID, AND ANTIBLOCKING AGENT; PLASTER, PAINTS, ADHESIVES WACKER CHEMIE GMBH (DE) 2001-06-05 US disclosed
JP-2001019516-A CEMENT ADMIXTURE AND CEMENT COMPOSITION DENKI KAGAKU KOGYO KK 2001-01-23 JP disclosed
EP-1029018-A1 APPLICATION OF MICROCAPSULES AS LATENT HEAT ACCUMULATORS BASF AKTIENGESELLSCHAFT (DE) 2000-08-23 EP disclosed
WO-1999024525-A1 APPLICATION OF MICROCAPSULES AS LATENT HEAT ACCUMULATORS BASF AKTIENGESELLSCHAFT (DE) 1999-05-20 WO disclosed
CN-1208427-A Re-dispersible polymer powder and aqueous polymer dispersions obtained from it WACKER CHEMIE GMBH (DE) 1999-02-17 CN disclosed
US-5498665-A Use of polypropylene glycol as a shrinkage-reducing additive in dispersion powder compositions for construction materials WACKER-CHEMIE GMBH (DE) 1996-03-12 US disclosed
US-5446125-A Dissolving novolak resist in a solvent, contacting with cation exchange and chelate resins, separating chelate and ion exchange resins from novolak OCG MICROELECTRONIC MATERIALS, INC. (US) 1995-08-29 US disclosed
EP-0407889-A1 Polymer powder redispersable in water, obtainable by spraying aqueous polymer dispersions and its application as additive in hydraulic binders BASF Aktiengesellschaft (DE) 1991-01-16 EP disclosed
EP-0324345-A1 Method for water-proofing leather, furs and synthetic leathers BASF Aktiengesellschaft (DE) 1989-07-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130046103-A1 PREPARATION OF BENZOFURANS AND USE THEREOF AS SYNTHETIC INTERMEDIATES CYP2F1, CYP4F3, CYP2D6 AURKA 2303/4885AURKB 2533/4885CDK2 1935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.