Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15722779 | 0.90 | GBA1 (0.37) | EEDKMT2AGBA1MEN1CHRNB2 | |
| SCHEMBL7192200 | 0.82 | MEN1 (0.41) | KMT2AMEN1CHRNB2CHRNA4POLB | |
| SCHEMBL8965756 | 0.82 | MEN1 (0.41) | KMT2AMEN1CHRNB2CHRNA4POLB | |
| SCHEMBL253686 | 0.72 | POLB (0.44) | KMT2AGBA1MEN1SLC6A2SLC6A4 | |
| SCHEMBL14986054 | 0.71 | MEN1 (0.49) | KMT2AGBA1MEN1CHRNB2CHRNA4 | |
| SCHEMBL15749661 | 0.68 | SLC6A2 (0.38) | KMT2AGBA1MEN1SLC6A2SLC6A4 | |
| SCHEMBL2884183 | 0.68 | MEN1 (0.39) | KMT2AMEN1CHRNB2CHRNA4 | |
| SCHEMBL8056836 | 0.67 | HTT (0.42) | CHRNB2CHRNA4POLB | |
| SCHEMBL8965651 | 0.67 | HTT (0.42) | CHRNB2CHRNA4POLB | |
| Bromide SCHEMBL15709541 | 0.67 | SLC6A2 (0.37) | KMT2AGBA1MEN1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |