Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20375134 | 1.00 | CYP1A2 (0.52) | CYP1A2CYP2C19KMT2ACA1CA2 | |
| SCHEMBL19166663 | 0.92 | CYP1A2 (0.46) | CYP1A2CYP2C19KMT2ACA1CA2 | |
| SCHEMBL18680424 | 0.90 | CYP1A2 (0.44) | CYP1A2CYP2C19KMT2ACA1CA2 | |
| SCHEMBL430482 | 0.87 | CXCR4 (0.40) | CYP1A2CYP2C19KMT2ACA1CA2 | |
| SCHEMBL10543159 | 0.87 | CYP1A2 (0.61) | CYP1A2CYP2C19KMT2ACA1CA2 | |
| SCHEMBL17576127 | 0.87 | CYP1A2 (0.42) | CYP1A2CYP2C19KMT2ACA1CA2 | |
| SCHEMBL16769809 | 0.86 | CA1 (0.49) | CYP1A2CYP2C19KMT2ACA1CA2 | |
| SCHEMBL9913709 | 0.86 | CA1 (0.49) | CYP1A2CYP2C19KMT2ACA1CA2 | |
| SCHEMBL18757549 | 0.86 | CA1 (0.41) | CYP1A2CYP2C19KMT2ACA1CA2 | |
| SCHEMBL18680447 | 0.85 | TLR8 (0.46) | CYP1A2CYP2C19KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016946-A1 | DRUG-LOADED MACROMOLECULE AND PREPARATION METHOD THEREFOR | SHANGHAI SHENGDI PHARMACEUTICAL CO., LTD. (CN) | 2024-01-18 | — | — | US | disclosed |
| US-8258259-B2 | Macromolecular compounds having controlled stoichiometry | STARPHARMA PTY LIMITED (AU) | 2012-09-04 | — | — | US | disclosed |
| US-20120063976-A1 | METHODS OF REMOVING CARBON DIOXIDE AND SORBENTS FOR SAME | BATTELLE ENERGY ALLIANCE, LLC (US) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016946-A1 | DRUG-LOADED MACROMOLECULE AND PREPARATION METHOD THEREFOR | MRPL38, MRPS27, MRPS18A | CYP1A2 2683/4885CYP2C19 1749/4885KMT2A 3804/4885 |
| US-20120063976-A1 | METHODS OF REMOVING CARBON DIOXIDE AND SORBENTS FOR SAME | CHRM2, CHRM1, CHRM3 | CYP1A2 2299/4885CYP2C19 2254/4885KMT2A 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.