SCHEMBL4282871

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4280770	0.93	FFAR1 (0.34)	FFAR1PPARGPPARAPDE4APDE4B
	SCHEMBL4271309	0.93	PDE4B (0.38)	FFAR1PPARGPPARAPDE4APDE4B
	SCHEMBL4276856	0.92	PDE4B (0.35)	FFAR1PPARGPPARAPDE4APDE4B
	SCHEMBL4277067	0.90	FFAR1 (0.34)	FFAR1PPARGPPARAMAPTRXFP1
	SCHEMBL4277707	0.90	S1PR1 (0.37)	FFAR1PPARGPPARAPDE4APDE4B
	SCHEMBL4278848	0.90	S1PR1 (0.36)	PPARGPPARAPDE4APDE4BPDE4C
	SCHEMBL4281548	0.90	PDE4A (0.37)	PPARGPPARAPDE4APDE4BPDE4C
	SCHEMBL4271374	0.90	S1PR1 (0.37)	FFAR1PPARGPPARAPDE4APDE4B
	SCHEMBL4282792	0.88	PDE4D (0.34)	FFAR1PPARGPPARAPDE4APDE4B
	SCHEMBL4277733	0.88	PDE4D (0.32)	FFAR1PPARGPPARAPDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.