Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 2/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 6/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2928121 | 0.84 | GSK3B (0.32) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL2926625 | 0.84 | CNR1 (0.33) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| Hydrochloric Acid SCHEMBL4283482 | 0.84 | GSK3B (0.32) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL2935929 | 0.73 | GSK3B (0.33) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL2934351 | 0.72 | CCR6 (0.41) | GSK3BTMPRSS4DPP4CCR6 | |
| SCHEMBL13300067 | 0.71 | GSK3B (0.59) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL13300098 | 0.69 | GSK3B (0.51) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL13300243 | 0.69 | GSK3B (0.56) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL6069368 | 0.68 | GSK3B (0.51) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL2931661 | 0.68 | AHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258877-A1 | TRIAZOLOTRIAZINES AND TRIAZOLOPYRAZINES AND THEIR USE | BAYER HEALTHCARE AG (DE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258877-A1 | TRIAZOLOTRIAZINES AND TRIAZOLOPYRAZINES AND THEIR USE | THPO, IL5, TPMT | GSK3B 2707/4885CCNB2 1130/4885CDK1 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.