Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 8/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10108616 | 0.78 | KDM4E (0.70) | KDM4EALDH1A1AOC3ADRA2CLMNA | |
| SCHEMBL5962393 | 0.78 | KDM4E (0.70) | KDM4EALDH1A1AOC3ADRA2CLMNA | |
| SCHEMBL3874299 | 0.78 | KDM4E (0.70) | KDM4EALDH1A1AOC3ADRA2CLMNA | |
| SCHEMBL13741557 | 0.78 | KDM4E (0.70) | KDM4EALDH1A1AOC3ADRA2CLMNA | |
| SCHEMBL5962400 | 0.78 | KDM4E (0.70) | KDM4EALDH1A1AOC3ADRA2CLMNA | |
| SCHEMBL12785309 | 0.78 | HTR2A (0.48) | KDM4EALDH1A1AOC3ADRA2CADRA2A | |
| SCHEMBL13532093 | 0.78 | HTR2A (0.48) | KDM4EALDH1A1AOC3ADRA2CADRA2A | |
| SCHEMBL13532096 | 0.78 | HTR2A (0.48) | KDM4EALDH1A1AOC3ADRA2CADRA2A | |
| SCHEMBL1674631 | 0.78 | KDM4E (0.58) | KDM4EALDH1A1AOC3ADRA2CLMNA | |
| SCHEMBL24414398 | 0.77 | AOC3 (0.63) | KDM4EALDH1A1AOC3ADRA2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582799-A2 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (S)-3-(1-AMINOETHYL)-PHENOL | Codexis, Inc. (US) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011159910-A2 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (S)-3-(1-AMINOETHYL)-PHENOL | CODEXIS, INC. (US) | 2011-12-22 | — | — | WO | disclosed |