SCHEMBL4284038

SCHEMBL4284038

[O]C(c1ccccc1)C(c1ccccc1)(c1ccccc1)C([O])(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
ACP3 P15309 2/20 0.34
PTPN1 P18031 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
CYP2D6 P10635 1/20 0.32
PTPN5 P54829 1/20 0.32
LMNA P02545 2/20 0.31
MAPK1 P28482 1/20 0.31
DPP4 P27487 2/20 0.31
KCNN4 O15554 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4274915 0.76 SRC (0.38) SRCCES2CES1ACP3PTPN1
SCHEMBL28837273 0.73 SRC (0.39) SRCCES2CES1ACP3PTPN1
SCHEMBL4274555 0.73 SRC (0.39) SRCCES2CES1ACP3PTPN1
SCHEMBL4269900 0.71 KCNN4 (0.47) PTPN1CA1CA2CA5ACA9
SCHEMBL6572027 0.68 CNR1 (0.35) SRCACP3CA1CA2CA5A
SCHEMBL6571171 0.67 CYP1A2 (0.42) CES2CES1ACP3CYP2D6
SCHEMBL4279202 0.67 SRC (0.34) SRCCES2CES1ACP3PTPN1
SCHEMBL17956469 0.66 TSHR (0.43) SRCCES2CES1CYP2D6LMNA
SCHEMBL5042134 0.66 ATM (0.42) SRCCES2CES1CYP2D6DPP4
SCHEMBL382252 0.66 ACP3 (0.42) SRCCES2CES1ACP3PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615660-B2 Production process of alkoxy-titanium complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-11-10 US disclosed
US-20080306293-A1 Production Process of Alkoxy-Titanium Complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-12-11 US disclosed
EP-1845101-A1 METHOD FOR PRODUCING ALKOXYTITANIUM COMPLEX Sumitomo Chemical Company, Limited (JP) 2007-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080306293-A1 Production Process of Alkoxy-Titanium Complex ABL1, H1-10, ALK SRC 1126/4885CES2 3184/4885CES1 3119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.