Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.34 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603636 | 1.00 | MAPT (0.40) | MAPTLMNAKDM4EDUSP3MEN1 | |
| Acetone SCHEMBL2803680 | 0.97 | MAPT (0.38) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL21645267 | 0.89 | MAPT (0.55) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL10795570 | 0.89 | MAPT (0.55) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL21645312 | 0.88 | MAPT (0.58) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL21645269 | 0.88 | MAPT (0.58) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL539662 | 0.88 | MAPT (0.58) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL21645279 | 0.88 | MAPT (0.58) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL10765993 | 0.88 | MAPT (0.58) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL6025493 | 0.88 | MAPT (0.58) | MAPTLMNAKDM4EDUSP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722864-B2 | Glycosylated acetaminophen pro-drug analogs | NuTek Pharma Ltd. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20120022012-A1 | Glycosylated Acetaminophen Pro-Drug Analogs | NuTek Pharma Ltd. | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022012-A1 | Glycosylated Acetaminophen Pro-Drug Analogs | UGT1A3, GCG, UGT1A1 | MAPT 2243/4885LMNA 1396/4885KDM4E 4019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.