Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771091 | 0.80 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL28868714 | 0.79 | MAOB (0.66) | MAOBAKR1C1LMNAHTTSLC6A2 | |
| SCHEMBL5437376 | 0.79 | MAOB (0.47) | MAOBAKR1C1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11079999 | 0.78 | MAOB (0.46) | MAOBAKR1C1LMNAHTTSLC6A2 | |
| SCHEMBL11077137 | 0.78 | MAOB (0.46) | MAOBAKR1C1LMNAHTTSLC6A2 | |
| SCHEMBL10651717 | 0.78 | MAOB (0.46) | MAOBAKR1C1LMNAHTTSLC6A2 | |
| SCHEMBL7549278 | 0.76 | CHRM1 (0.59) | MAOBAKR1C1SLC6A4 | |
| SCHEMBL15754675 | 0.76 | CHRM1 (0.59) | MAOBAKR1C1SLC6A4 | |
| SCHEMBL3556347 | 0.75 | MAOB (0.44) | MAOBAKR1C1LMNAHTTSLC6A2 | |
| SCHEMBL3745740 | 0.75 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150660-A1 | A PROCESS FOR THE PREPARATION OF ARYLCYCLOPROPANE CARBOXYLIC CARBONITRILES, AND COMPOUNDS DERIVED THEREFROM | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-12-17 | — | — | WO | disclosed |