Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 18/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279367 | 0.91 | AGPAT2 (1.00) | AGPAT2NPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6640849 | 0.89 | AGPAT2 (0.80) | AGPAT2NPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13880211 | 0.86 | AGPAT2 (1.00) | AGPAT2NPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13880171 | 0.84 | AGPAT2 (1.00) | AGPAT2NPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4279091 | 0.84 | AGPAT2 (0.85) | AGPAT2NPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13892054 | 0.81 | AGPAT2 (0.89) | AGPAT2NPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13880263 | 0.81 | AGPAT2 (0.75) | AGPAT2NPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13880138 | 0.80 | AGPAT2 (1.00) | AGPAT2 | |
| SCHEMBL13880351 | 0.80 | AGPAT2 (0.72) | AGPAT2NPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2410666 | 0.80 | NPC1 (0.77) | AGPAT2NPC1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099183-A1 | PYRIMIDINES AND USES THEREOF | CELL THERAPEUTICS, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| US-7419984-B2 | Pyrimidines and uses thereof | CELL THERAPEUTICS, INC. (US) | 2008-09-02 | — | — | US | disclosed |
| US-20040204386-A1 | Pyrimidines and uses thereof | CELL THERAPEUTICS, INC. | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204386-A1 | Pyrimidines and uses thereof | LPCAT3, LPCAT1, APRT | AGPAT2 100/4885NPC1 1406/4885CYP1A2 4325/4885 |
| US-20090099183-A1 | PYRIMIDINES AND USES THEREOF | LPCAT3, LPCAT1, APRT | AGPAT2 94/4885NPC1 1299/4885CYP1A2 4519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.