Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.38 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PTGFR | P43088 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430421 | 0.93 | KDM4E (0.39) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL429938 | 0.91 | GRIN1 (0.37) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL427443 | 0.90 | IKBKB (0.40) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL16204000 | 0.87 | KDM4E (0.39) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL427482 | 0.87 | IKBKB (0.39) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL427477 | 0.87 | IKBKB (0.39) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL430745 | 0.87 | IKBKB (0.39) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL427461 | 0.87 | IKBKB (0.41) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL428740 | 0.87 | IKBKB (0.37) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL427534 | 0.86 | IKBKB (0.38) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2375898-B1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-16 | — | — | EP | disclosed |
| US-8889595-B2 | Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-18 | — | — | US | disclosed |
| US-8889595-B2 | Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-18 | — | — | US | disclosed |
| US-20120065064-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120065064-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
| WO-2010069834-A1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065064-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP4X1 | IKBKB 4311/4885PRKAG1 3397/4885PRKAA1 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.