Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285603 | 1.00 | ESR2 (0.34) | ESR2ESR1CYP3A4CYP2C9GABRA1 | |
| SCHEMBL1531796 | 0.85 | ESR2 (0.51) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL1531798 | 0.85 | ESR2 (0.51) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL1509710 | 0.84 | HRH3 (0.45) | CYP3A4CYP2C9MAPTKMT2A | |
| SCHEMBL1509709 | 0.84 | HRH3 (0.45) | CYP3A4CYP2C9MAPTKMT2A | |
| SCHEMBL10938939 | 0.83 | SPHK1 (0.40) | SPHK1 | |
| SCHEMBL10687104 | 0.78 | GAA (0.35) | SPHK1KDM4EMAPTKMT2A | |
| SCHEMBL10684492 | 0.78 | GAA (0.35) | SPHK1KDM4EMAPTKMT2A | |
| SCHEMBL13096848 | 0.78 | GAA (0.35) | SPHK1KDM4EMAPTKMT2A | |
| SCHEMBL28605560 | 0.77 | KMT2A (0.41) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158483-A1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2009-12-30 | — | — | WO | disclosed |