⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419844 | 0.92 | — | — | |
| SCHEMBL8416747 | 0.90 | HSP90AA1 (0.64) | — | |
| SCHEMBL8419758 | 0.90 | HSP90AA1 (0.64) | — | |
| SCHEMBL8417882 | 0.90 | HSP90AA1 (0.64) | — | |
| SCHEMBL8417943 | 0.90 | HSP90AA1 (0.64) | — | |
| SCHEMBL8419953 | 0.90 | HSP90AA1 (0.64) | — | |
| SCHEMBL8417911 | 0.90 | HSP90AA1 (0.64) | — | |
| SCHEMBL8417931 | 0.90 | HSP90AA1 (0.64) | — | |
| SCHEMBL20678402 | 0.90 | HSP90AA1 (0.64) | — | |
| SCHEMBL8417899 | 0.90 | HSP90AA1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970638-B | Method for catalytically synthesizing chiral quinolinone compound with high enantioselectivity | 扬州大学 | 2022-05-31 | — | — | CN | claimed |
| CN-109970638-A | A kind of method of high enantioselectivity catalytically synthesizing chiral quinolinone compounds | 扬州大学 | 2019-07-05 | — | — | CN | claimed |
| CN-1346351-A | 1,2-benzothiazepines for the treatment of hyperlipidemic diseases | SEARLE & CO (US) | 2002-04-24 | — | — | CN | claimed |
| WO-1998027051-A9 | CATALYTIC ASYMMETRIC AMIDOHYDROXYLATION OF OLEFINS WITH N-HALO CARBOXAMIDES | — | 1998-11-12 | — | — | WO | claimed |
| WO-1998027051-A2 | CATALYTIC ASYMMETRIC AMIDOHYDROXYLATION OF OLEFINS WITH N-HALO CARBOXAMIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-25 | — | — | WO | claimed |
| CN-109970638-A | A kind of method of high enantioselectivity catalytically synthesizing chiral quinolinone compounds | 扬州大学 | 2019-07-05 | — | — | CN | disclosed |
| CN-109970638-A | A kind of method of high enantioselectivity catalytically synthesizing chiral quinolinone compounds | 扬州大学 | 2019-07-05 | — | — | CN | disclosed |
| US-8217001-B2 | Modification of feeding behavior | IMPERIAL INNOVATIONS LIMITED | 2012-07-10 | — | — | US | disclosed |
| US-20090209461-A1 | MODIFICATION OF FEEDING BEHAVIOR | IMPERIAL COLLEGE INNOVATIONS LTD. (GB) | 2009-08-20 | — | — | US | disclosed |
| EP-0781801-B1 | Silica-filled rubber compositions containing dialkyleneamide polysulfides | GOODYEAR TIRE & RUBBER (US) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998027051-A9 | CATALYTIC ASYMMETRIC AMIDOHYDROXYLATION OF OLEFINS WITH N-HALO CARBOXAMIDES | — | 1998-11-12 | — | — | WO | disclosed |
| WO-1998027051-A2 | CATALYTIC ASYMMETRIC AMIDOHYDROXYLATION OF OLEFINS WITH N-HALO CARBOXAMIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-25 | — | — | WO | disclosed |
| EP-0781801-A1 | Silica-filled rubber compositions containing dialkyleneamide polysulfides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5641820-A | SULFUR VULCANIZABLE ELASTOMERS WITH COUPLING AGENTS, FOR TIRE TREADS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-06-24 | — | — | US | disclosed |
| EP-0458197-A2 | Use of N-haloamides as photoinitiators for free-radical polymerizations | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1991-11-27 | — | — | EP | disclosed |