Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24454273 | 0.88 | HRH4 (0.51) | HRH4HRH3 | |
| SCHEMBL18551575 | 0.87 | HRH4 (0.49) | HRH4 | |
| SCHEMBL26748827 | 0.85 | HRH4 (0.50) | HRH4 | |
| SCHEMBL19513509 | 0.84 | HRH4 (0.62) | HRH4HRH3 | |
| SCHEMBL4278748 | 0.83 | GPBAR1 (0.47) | HRH4HRH3 | |
| Hydrochloric Acid SCHEMBL7229220 | 0.80 | HRH4 (0.44) | HRH4 | |
| SCHEMBL17696424 | 0.80 | GRIN2D (0.49) | HRH4 | |
| SCHEMBL18752414 | 0.80 | GRIN2D (0.49) | HRH4 | |
| SCHEMBL16785555 | 0.80 | GRIN2D (0.49) | HRH4 | |
| SCHEMBL17696421 | 0.80 | GRIN2D (0.49) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689868-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | Arvinas Operations, Inc. (US) | 2020-08-05 | — | — | EP | disclosed |
| WO-2018102725-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | Arvinas, Inc. (US) | 2018-06-07 | — | — | WO | disclosed |
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |