SCHEMBL428751

SCHEMBL428751

NN1CCNC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28444039 0.97
Methane SCHEMBL28352715 0.97
SCHEMBL6056256 0.81
SCHEMBL104481 0.79
SCHEMBL2254698 0.77
SCHEMBL15855949 0.76 HIF1A (0.43)
Bromide SCHEMBL4189519 0.76
SCHEMBL31047466 0.76
SCHEMBL2035218 0.76 HIF1A (0.43)
Hydrochloric Acid SCHEMBL19547768 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106317126-B Benzene oxygen 2- imine imidazole alkane metal complex and its preparation method and application 东华大学 2019-01-15 CN claimed
CN-106317126-A Phenoxy-2-iminoimidazolidine metal complex and preparation method and application thereof 东华大学 2017-01-11 CN claimed
EP-1730205-B1 POLIMERIZATION CATALYST COMPRISING AN AMIDINE LIGAND LANXESS ELASTOMERS BV (NL) 2012-09-26 EP claimed
US-20100256132-A1 IL-12 MODULATORY COMPOUNDS SYNTA PHARMACEUTICALS CORPORATION (US) 2010-10-07 US claimed
EP-1765325-A4 2-SUBSTITUTED HETEROARYL COMPOUNDS SYNTA PHARMACEUTICALS CORP (US) 2009-08-12 EP claimed
US-20090012246-A1 Polymerization Catalyst Comprising Amidine Ligand DMS IP ASSETS B.V. (NL) 2009-01-08 US claimed
JP-2007529584-A 2007-10-25 JP claimed
WO-2007100759-A2 METHOD FOR TREATING COMMON VARIABLE IMMUNODEFICIENCY SYNTA PHARMACEUTICALS CORP. (US) 2007-09-07 WO claimed
EP-1819341-A2 IL-12 MODULATORY COMPOUNDS Synta Pharmaceuticals Corporation (US) 2007-08-22 EP claimed
EP-1765325-A2 2-SUBSTITUTED HETEROARYL COMPOUNDS Synta Pharmaceuticals Corporation (US) 2007-03-28 EP claimed
US-20060063739-A1 2-Substituted heteroaryl compounds LSI FINANCING LLC, AS ADMINISTRATIVE AGENT 2006-03-23 US claimed
WO-2006007532-A2 2-SUBSTITUTED HETEROARYL COMPOUNDS SYNTA PHARMACEUTICALS CORP. (US) 2006-01-19 WO claimed
WO-2005090418-A1 POLIMERIZATION CATALYST COMPRISING AN AMIDINE LIGAND DSM IP ASSETS B.V. (NL) 2005-09-29 WO claimed
EP-1412327-A2 INHIBITORS OF PROTEIN KINASE FOR THE TREATMENT OF DISEASE LG Biomedical Institute (US) 2004-04-28 EP claimed
US-20030187007-A1 Inhibitors of protein kinase for the treatment of disease LG BIOMEDICAL INSTITUTE 2003-10-02 US claimed
WO-2002096867-A2 INHIBITORS OF PROTEIN KINASE FOR THE TREATMENT OF DISEASE LG BIOMEDICAL INSTITUTE (US) 2002-12-05 WO claimed
US-5512588-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-04-30 US claimed
EP-0107306-B1 IMIDAZOLINE DERIVATIVES BEECHAM GROUP PLC (GB) 1986-04-30 EP claimed
US-4505926-A GASTROINTESTINAL DISORDERS ANTIDIARRHEA BEECHAM GROUP P.L.C. (GB) 1985-03-19 US claimed
EP-0107306-A1 Imidazoline derivatives BEECHAM GROUP PLC (GB) 1984-05-02 EP claimed