Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | EYA2 | O00167 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438 | 0.87 | — | — | |
| SCHEMBL3946913 | 0.87 | MAPT (0.44) | KDM4EMAPTABCC4KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4732743 | 0.85 | — | — | |
| Ammonia Solution, Strong SCHEMBL28182267 | 0.85 | — | — | |
| Water SCHEMBL7160929 | 0.85 | — | — | |
| SCHEMBL7184515 | 0.85 | — | — | |
| SCHEMBL10869584 | 0.85 | — | — | |
| Oxalic Acid SCHEMBL28044433 | 0.83 | MAPT (0.41) | KDM4EMAPTABCC4KMT2ASMN1; SMN2 | |
| SCHEMBL5826308 | 0.82 | KDM4E (0.38) | KDM4EMAPTABCC4KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2050506 | 0.81 | KDM4E (0.37) | KDM4EMAPTABCC4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334412-B2 | Process for preparing 3-(methylthio)propanal | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20120022295-A1 | PROCESS FOR PREPARING 3-(METHYLTHIO)PROPANAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022295-A1 | PROCESS FOR PREPARING 3-(METHYLTHIO)PROPANAL | PTMA, TMT1A, MGMT | KDM4E 4468/4885MAPT 826/4885ABCC4 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.