SCHEMBL4288227

SCHEMBL4288227

O=C[N+]1(O)CCN(O)C1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL757874 0.65
SCHEMBL1618441 0.65
SCHEMBL16738339 0.60
SCHEMBL15287005 0.52 CYP3A4 (0.38)
SCHEMBL30005 0.52
SCHEMBL29941563 0.48 KDM4E (0.41)
Fluoride SCHEMBL9547349 0.48
SCHEMBL28919236 0.45
SCHEMBL9361606 0.42
SCHEMBL27634354 0.42

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4619999-A Aliphatic isocyanate compounds AMERICAN CYANAMID COMPANY (US) 1986-10-28 US claimed
EP-0120193-A1 Aliphatic isocyanate compounds AMERICAN CYANAMID COMPANY (US) 1984-10-03 EP claimed
EP-1797947-B1 Encapsulated active material with reduced formaldehyde potential INT FLAVORS & FRAGRANCES INC (US) 2013-03-27 EP disclosed
EP-2545988-A2 Encapsulated active material with reduced formaldehyde potential International Flavors & Fragrances, Inc. (US) 2013-01-16 EP disclosed
US-20090258042-A1 Encapsulated Active Materials Containing Adjunct Crosslinkers INTERNATIONAL FLAVORS & FRAGRANCES INC. 2009-10-15 US disclosed
US-20070138674-A1 ENCAPSULATED ACTIVE MATERIAL WITH REDUCED FORMALDEHYDE POTENTIAL INTERNATIONAL FLAVORS & FRAGRANCES INC. 2007-06-21 US disclosed
US-20070138671-A1 Encapsulated active material with reduced formaldehyde potential INTERNATIONAL FLAVORS & FRAGRANCES INC. 2007-06-21 US disclosed
EP-1797947-A2 Encapsulated active material with reduced formaldehyde potential INTERNATIONAL FLAVORS &amp; FRAGRANCES, INC. (US) 2007-06-20 EP disclosed
US-6881708-B2 Compositions for solving lost circulation problems HALLIBURTON ENERGY SERVICES, INC. (US) 2005-04-19 US disclosed
US-20030092582-A1 Compositions for solving lost circulation problems REDDY B RAGHAVA (US) 2003-05-15 US disclosed
US-6508306-B1 Sealing subterranean well bores using mixtures of butadiene-styrene copolymer emulsions, melamine-formaldehyde resins and acid catalysts, then contacting with drilling fluids to restore hydrostatic pressure; dimensional stability; hardness HALLIBURTON ENERGY SERVICES, INC. 2003-01-21 US disclosed
US-5721309-A CROSSLINKABLE ACRYLIC POLYMER; AN AMINO RESIN CROSSLINKING AGENT; A SILICA FLATTING AGENT AND AMINOETHYL-AMINOPROPYL-DIMETHOXY-SILYL-END-BLOCKED POLYDIMETHYLSILOXANE GENCORP INC. (US) 1998-02-24 US disclosed
US-5594061-A ACRYLIC LATEX COATINGS WITH REDUCED GLOSS AND SHELF STABILITY GENCORP INC. (US) 1997-01-14 US disclosed
EP-0671448-A1 Aqueous coating for vinyl chloride polymer substrate GENCORP INC. (US) 1995-09-13 EP disclosed
US-4929494-A METALLIC FOIL LAMINATES FOR ELECTRONICS SHOWA DENKO KABUSHIKI KAISHA (JP) 1990-05-29 US disclosed
EP-0266775-A2 Laminates SHOWA DENKO KABUSHIKI KAISHA (JP) 1988-05-11 EP disclosed