SCHEMBL4288361

SCHEMBL4288361

CC(=O)OCc1cc(F)c(Cc2ccc(OC3CC3)cc2)c(O[C@@H]2O[C@H]([C@@H](C)O)[C@@H](O)[C@H](O)[C@H]2O)c1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 1/20 0.34
▸ SLC5A2 P31639 16/20 0.34
▸ SLC5A1 P13866 15/20 0.34
▸ APP P05067 1/20 0.33
▸ ACACB O00763 1/20 0.32
▸ PTGS1 P23219 1/20 0.32
▸ PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4284267 0.91 SLC5A2 (0.41) SLC5A2SLC5A1
SCHEMBL4292210 0.91 SLC5A2 (0.36) SLC5A2SLC5A1ACACB
SCHEMBL4289187 0.90 SLC5A2 (0.39) SLC5A2SLC5A1
SCHEMBL4285652 0.89 SLC5A2 (0.39) SLC5A2SLC5A1
SCHEMBL4281191 0.89 SLC5A2 (0.37) SLC5A2SLC5A1
SCHEMBL4290264 0.84 SLC5A2 (0.40) SLC5A2SLC5A1
SCHEMBL4284485 0.81 SLC5A2 (0.46) SLC5A2SLC5A1
SCHEMBL4294434 0.81 SLC5A2 (0.41) SLC5A2SLC5A1
SCHEMBL4288364 0.80 HTR2A (0.34) HTR2ASLC5A2SLC5A1APPACACB
SCHEMBL4282745 0.80 SLC5A2 (0.40) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 — — US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 HTR2A 910/4885SLC5A2 2/4885SLC5A1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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