Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 6/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100153 | 0.89 | SLC7A5 (0.58) | SLC7A5ANPEPERAP1SLC1A3SLC1A2 | |
| SCHEMBL995721 | 0.89 | SLC7A5 (0.58) | SLC7A5ANPEPERAP1SLC1A3SLC1A2 | |
| Threonine SCHEMBL3495953 | 0.87 | SLC7A5 (0.46) | SLC7A5ANPEPERAP1PTGS1SLC7A11 | |
| SCHEMBL1964879 | 0.85 | PTGS1 (0.55) | ANPEPPTGS1SLC7A11ENPEP | |
| SCHEMBL20657045 | 0.85 | PTGS1 (0.55) | ANPEPPTGS1SLC7A11ENPEP | |
| SCHEMBL7676359 | 0.83 | SLC7A5 (0.52) | SLC7A5ANPEPERAP1SLC1A3SLC1A2 | |
| SCHEMBL1585736 | 0.83 | SLC7A5 (0.52) | SLC7A5ANPEPERAP1SLC1A3SLC1A2 | |
| SCHEMBL14485413 | 0.83 | SLC7A5 (0.52) | SLC7A5ANPEPERAP1SLC1A3SLC1A2 | |
| SCHEMBL7361839 | 0.83 | SLC7A5 (0.52) | SLC7A5ANPEPERAP1SLC1A3SLC1A2 | |
| SCHEMBL1675943 | 0.83 | PTGS1 (0.44) | SLC7A5ANPEPERAP1PTGS1SLC7A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018156-A1 | COMPOSITIONS AND METHODS FOR TREATING B- CELL MALIGNANCIES | Chimeros, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2008108776-A1 | COMPOSITIONS AND METHODS FOR TREATING B- CELL MALIGNANCIES | CHIMEROS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |