SCHEMBL4288599

SCHEMBL4288599

CCCOc1c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cn(C)c(CN(C)C)n2)cc(OC)cc1OC

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 18/20 0.67
PIK3CD O00329 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10044516 0.93 PIK3CG (0.73) PIK3CGPIK3CD
SCHEMBL2732907 0.92 PIK3CG (0.70) PIK3CGPIK3CD
SCHEMBL4298874 0.92 PIK3CG (0.72) PIK3CGPIK3CD
SCHEMBL4291889 0.91 PIK3CG (0.62) PIK3CGPIK3CD
SCHEMBL2734095 0.91 PIK3CG (0.62) PIK3CGPIK3CD
SCHEMBL4289262 0.90 PIK3CG (0.58) PIK3CGPIK3CD
SCHEMBL18175018 0.87 PIK3CG (0.70) PIK3CGPIK3CD
SCHEMBL4286767 0.87 PIK3CG (0.63) PIK3CGPIK3CD
SCHEMBL4302931 0.85 PIK3CG (0.53) PIK3CGPIK3CD
SCHEMBL3582406 0.83 PIK3CG (0.85) PIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012052102-A1 QUINOXALINE DERIVATES MERCK PATENT GMBH (DE) 2012-04-26 WO disclosed