Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decane SCHEMBL4288830 | 0.97 | TSHR (0.53) | TSHRTHRBCA1CA6CA5A | |
| Pentane SCHEMBL88249 | 0.86 | TSHR (0.50) | TSHRTHRBCA1CA6CA5A | |
| Octane SCHEMBL28818930 | 0.85 | TSHR (0.67) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Pentadecane SCHEMBL28249592 | 0.85 | TSHR (0.67) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Octane SCHEMBL23933879 | 0.85 | TSHR (0.67) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Decane SCHEMBL23933878 | 0.85 | TSHR (0.67) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hexadecane SCHEMBL28526152 | 0.85 | TSHR (0.67) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Dodecane SCHEMBL28062385 | 0.85 | TSHR (0.67) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL8541557 | 0.84 | TSHR (0.40) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL14746519 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2138527-A1 | Nanoparticle, method for producing a nanoparticle, nanoparticle system and its use | Freie Universität Berlin (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2009156455-A1 | METHOD FOR PRODUCING A NANOPARTICLE, NANOPARTICLE, NANOPARTICLE SYSTEM AND ITS USE | FREIE UNIVERSITÄT BERLIN (DE) | 2009-12-30 | — | — | WO | disclosed |
| EP-1565443-A4 | ACETYL 2-HYDROXY-1,3 DIAMINOALKANES | ELAN PHARM INC (US) | 2007-07-18 | — | — | EP | disclosed |
| EP-1751091-A2 | 2-AMINO- AND 2-THIO-SUBSTITUTED 1,3-DIAMINOPROPANES | Elan Pharmaceuticals, Inc. (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005095326-A2 | 2-AMINO- AND 2-THIO-SUBSTITUTED 1,3-DIAMINOPROPANES | ELAN PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | disclosed |
| EP-1565443-A2 | ACETYL 2-HYDROXY-1,3 DIAMINOALKANES | Elan Pharmaceuticals, Inc. (US) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004024081-A2 | ACETYL 2-HYDROXY-1,3 DIAMINOALKANES | ELAN PHARMACEUTICALS, INC. (US) | 2004-03-25 | — | — | WO | disclosed |