Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4293129 | 1.00 | TYR (0.62) | TYRCA12CA9AKR1B1NR1H3 | |
| SCHEMBL4298856 | 1.00 | TYR (0.62) | TYRCA12CA9AKR1B1NR1H3 | |
| SCHEMBL4287064 | 1.00 | TYR (0.62) | TYRCA12CA9AKR1B1NR1H3 | |
| SCHEMBL15196950 | 0.86 | CA12 (0.54) | TYRCA12CA9AKR1B1NR1H3 | |
| SCHEMBL1491947 | 0.86 | CA12 (0.51) | TYRCA12CA9AKR1B1NR1H3 | |
| SCHEMBL10103003 | 0.86 | CA12 (0.54) | TYRCA12CA9AKR1B1NR1H3 | |
| SCHEMBL1491881 | 0.86 | CA12 (0.51) | TYRCA12CA9AKR1B1NR1H3 | |
| SCHEMBL7665014 | 0.85 | CA12 (0.50) | TYRCA12CA9AKR1B1NR1H3 | |
| SCHEMBL8829594 | 0.85 | CA12 (0.50) | TYRCA12CA9AKR1B1NR1H3 | |
| SCHEMBL788314 | 0.85 | CA12 (0.50) | TYRCA12CA9AKR1B1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090263339-A1 | AGENT FOR EXTERNAL APPLICATION TO THE SKIN | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKY (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1894558-A1 | AGENT FOR EXTERNAL APPLICATION TO THE SKIN | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2008-03-05 | — | — | EP | disclosed |