⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cysteine SCHEMBL29387447 | 1.00 | — | — | |
| Cysteine SCHEMBL7898895 | 1.00 | PTGS1 (1.00) | — | |
| Cysteine SCHEMBL29965523 | 1.00 | — | — | |
| Cysteine SCHEMBL95110 | 1.00 | — | — | |
| Cysteine SCHEMBL339562 | 1.00 | PTGS1 (1.00) | — | |
| Cysteine SCHEMBL5705426 | 1.00 | PTGS1 (1.00) | — | |
| Cysteine SCHEMBL5705430 | 1.00 | PTGS1 (1.00) | — | |
| Cysteine SCHEMBL1868335 | 1.00 | PTGS1 (1.00) | — | |
| Cysteine SCHEMBL21110883 | 1.00 | PTGS1 (1.00) | — | |
| Cysteine SCHEMBL30607088 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761784-B1 | IDENTIFICATION OF ERGOTHIONEINE TRANSPORTER AND THERAPEUTIC USES THEREOF | UNIVERSITÄT ZU KÖLN (DE) | 2016-10-26 | — | — | EP | disclosed |
| US-8492106-B2 | Identification methods for ergothioneine transporter modulators and therapeutic uses thereof | UNIVERSITAT ZU KOLN (DE) | 2013-07-23 | — | — | US | disclosed |
| US-20090214431-A1 | IDENTIFICATION OF ERGOTHIONEINE TRANSPORTER AND THERAPEUTIC USES THEREOF | UNIVERSITÄT ZU KOLN (DE) | 2009-08-27 | — | — | US | disclosed |
| US-20080107603-A1 | Neuroprotectant methods, compositions, and screening methods thereof | OXIS INTERNATIONAL, INC. | 2008-05-08 | — | — | US | disclosed |
| EP-1496893-A4 | NEUROPROTECTANT METHODS, COMPOSITIONS, AND SCREENING METHODS THEREOF | OXIS INT INC (US) | 2007-03-28 | — | — | EP | disclosed |
| EP-1761784-A2 | IDENTIFICATION OF ERGOTHIONEINE TRANSPORTER AND THERAPEUTIC USES THEREOF | UNIVERSITÄT ZU KÖLN (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005116657-A2 | IDENTIFICATION OF ERGOTHIONEINE TRANSPORTER AND THERAPEUTIC USES THEREOF | UNIVERSITÄT ZU KÖLN (DE) | 2005-12-08 | — | — | WO | disclosed |
| EP-1496893-A2 | NEUROPROTECTANT METHODS, COMPOSITIONS, AND SCREENING METHODS THEREOF | Oxis International, Inc. (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003082216-A9 | NEUROPROTECTANT METHODS, COMPOSITIONS, AND SCREENING METHODS THEREOF | OXIS INT INC (US) | 2004-03-04 | — | — | WO | disclosed |
| WO-2003099277-A1 | METHOD OF REDUCING INCIDENCE DIABETIC EMBRYOPATHY WITH L-ERGOTHIONEINE | OXIS INTERNATIONAL, INC. (US) | 2003-12-04 | — | — | WO | disclosed |
| WO-2003082216-A2 | NEUROPROTECTANT METHODS, COMPOSITIONS, AND SCREENING METHODS THEREOF | OXIS INTERNATIONAL, INC. (US) | 2003-10-09 | — | — | WO | disclosed |