Bromide

Bromide

SCHEMBL4290668

[Br-].[Br-].[Ni+2].c1ccc(P(c2ccccc2)c2ccccc2Oc2ccccc2P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
DRD1 P21728 2/20 0.37
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
TOP1 P11387 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28129929 0.96 CYP3A4 (0.50) CYP3A4TDP1DRD1ESR1ESR2
SCHEMBL101880 0.96 CYP3A4 (0.50) CYP3A4TDP1DRD1ESR1ESR2
SCHEMBL29375055 0.93 CYP3A4 (0.48) CYP3A4TDP1DRD1ESR1ESR2
Water SCHEMBL28249068 0.93 CYP3A4 (0.48) CYP3A4TDP1DRD1ESR1ESR2
SCHEMBL2142709 0.93 CYP3A4 (0.48) CYP3A4TDP1DRD1ESR1ESR2
SCHEMBL17674561 0.93 CYP3A4 (0.48) CYP3A4TDP1DRD1ESR1ESR2
SCHEMBL31059892 0.93 CYP3A4 (0.48) CYP3A4TDP1DRD1ESR1ESR2
SCHEMBL31153795 0.93 CYP3A4 (0.48) CYP3A4TDP1DRD1ESR1ESR2
Hydrochloric Acid SCHEMBL2126739 0.91 CYP3A4 (0.46) CYP3A4TDP1DRD1ESR1ESR2
SCHEMBL30015097 0.88 CYP3A4 (0.42) CYP3A4TDP1DRD1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114796591-A Cyanoacrylate medical adhesive and preparation method and application thereof 北京康派特医疗器械有限公司 2022-07-29 CN claimed
US-10471174-B2 Cyanoacrylate medical adhesive and preparation method and use thereof Shen, Wei (CN) 2019-11-12 US claimed
US-20190175782-A1 NOVEL CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN, WEI (CN) 2019-06-13 US claimed
EP-3335738-A1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF Shen, Wei (CN) 2018-06-20 EP claimed
US-7357921-B2 Hair cosmetic formualtion containing an acrylic or vinyl monomer capable of polymerizing by anionic polymerization in the presence of a nucleophilc agent L'OREAL (FR) 2008-04-15 US claimed
US-6413539-B1 BLOCK POLYMER POLY-MED, INC. 2002-07-02 US claimed
EP-0952171-A2 Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof Poly-Med Inc. (US) 1999-10-27 EP claimed
JP-54097636-A None JP disclosed
CN-114796591-A Cyanoacrylate medical adhesive and preparation method and application thereof 北京康派特医疗器械有限公司 2022-07-29 CN disclosed
US-20220011078-A1 POLYMER AMMUNITION ARTICLE DESIGNED FOR USE ACROSS A WIDE TEMPERATURE RANGE PCP TACTICAL, LLC (US) 2022-01-13 US disclosed
EP-3847411-A1 POLYMER AMMUNITION ARTICLE DESIGNED FOR USE ACROSS A WIDE TEMPERATURE RANGE PCP TACTICAL, LLC (US) 2021-07-14 EP disclosed
WO-2020028182-A1 POLYMER AMMUNITION ARTICLE DESIGNED FOR USE ACROSS A WIDE TEMPERATURE RANGE PCP TACTICAL, LLC (US) 2020-02-06 WO disclosed
CN-106620827-B Application of poly (diglyceride sebacate) 东华大学 2019-12-31 CN disclosed
US-20090264555-A1 Cyanoacrylate tissue adhesive formulations with multipurpose rheology modifiers POLY-MED, INC. 2009-10-22 US disclosed
EP-2065420-A1 METHOD FOR PRODUCING POLYARYLENE Sumitomo Chemical Company, Limited (JP) 2009-06-03 EP disclosed
US-7351426-B2 Polyester/cyanoacrylate tissue adhesive compositions POLY-MED, INC. (US) 2008-04-01 US disclosed
US-7351426-B2 Polyester/cyanoacrylate tissue adhesive compositions POLY-MED, INC. (US) 2008-04-01 US disclosed
US-20040199207-A1 Polyester/cyanoacrylate tissue adhesive compositions POLY-MED, INC. 2004-10-07 US disclosed
US-20040199207-A1 Polyester/cyanoacrylate tissue adhesive compositions POLY-MED, INC. 2004-10-07 US disclosed
JP-S5497636-A PREPARATION OF ADHESIVE TOAGOSEI CHEM IND CO LTD 1979-08-01 JP disclosed