Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FES | P07332 | 1/20 | 0.47 |
| ▸ | FER | P16591 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | FRK | P42685 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 10/20 | 0.42 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429177 | 0.86 | FES (0.47) | FESFERTYK2FRKSYK | |
| SCHEMBL429175 | 0.86 | FES (0.47) | FESFERTYK2FRKSYK | |
| SCHEMBL1603126 | 0.86 | FES (0.47) | FESFERTYK2FRKSYK | |
| SCHEMBL425563 | 0.81 | MAPT (0.45) | FESFERTYK2FRKSYK | |
| SCHEMBL425564 | 0.81 | MAPT (0.45) | FESFERTYK2FRKSYK | |
| SCHEMBL14530459 | 0.79 | FES (0.42) | FESFERTYK2FRKSYK | |
| SCHEMBL429464 | 0.79 | MAPT (0.43) | FESFERTYK2FRKSYK | |
| SCHEMBL429463 | 0.79 | MAPT (0.43) | FESFERTYK2FRKSYK | |
| SCHEMBL13759371 | 0.77 | MAPT (0.43) | FESFERTYK2FRKSYK | |
| SCHEMBL430738 | 0.77 | PIKFYVE (0.60) | FESFERTYK2FRKSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021434-A1 | METHOD FOR TREATING B CELL REGULATED AUTOIMMUNE DISORDERS | SYNTA PHARMACEUTICALS CORP. (US) | 2012-01-26 | — | — | US | disclosed |