Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 8/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 8/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 8/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4296169 | 0.91 | CSNK2A2 (0.48) | FFAR1CYP2C8CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3010999 | 0.89 | FFAR1 (0.51) | FFAR1CYP2C8CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL4293704 | 0.88 | FFAR1 (0.53) | FFAR1CYP2C8CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3001663 | 0.86 | CYP2C8 (0.55) | FFAR1CYP2C8CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3012615 | 0.83 | FFAR1 (0.63) | FFAR1CYP2C8CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3002383 | 0.81 | CYP2C8 (0.60) | FFAR1CYP2C8MAOAMAOBALOX5 | |
| SCHEMBL3008716 | 0.81 | CYP2C8 (0.53) | FFAR1CYP2C8CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL4293921 | 0.80 | CSNK2A2 (0.42) | CSNK2A2CSNK2BCSNK2A1ALOX5ESR2 | |
| SCHEMBL3013095 | 0.79 | CSNK2A2 (0.50) | FFAR1CYP2C8CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3002395 | 0.79 | CYP2C8 (0.61) | CYP2C8CSNK2A2CSNK2BCSNK2A1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | disclosed |