Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.69 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 11/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 8/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL5011502 | 1.00 | SLC7A5 (0.69) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL18249997 | 1.00 | SLC7A5 (0.69) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| D-Leucine SCHEMBL1537398 | 1.00 | SLC7A5 (0.69) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL3314487 | 1.00 | SLC7A5 (0.69) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL122270 | 1.00 | SLC7A5 (0.69) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| D-Leucine SCHEMBL1537401 | 1.00 | SLC7A5 (0.69) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL122271 | 1.00 | SLC7A5 (0.69) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL1537204 | 1.00 | SLC7A5 (0.69) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL1537205 | 1.00 | SLC7A5 (0.69) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| D-Leucine SCHEMBL14698277 | 1.00 | SLC7A5 (0.69) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9522198-B2 | Methods and compositions related to targeting tumors and wounds | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2016-12-20 | — | — | US | disclosed |
| EP-2510943-B1 | Methods and compositions related to targeting tumors and wounds | BURNHAM INST MEDICAL RESEARCH (US) | 2016-04-20 | — | — | EP | disclosed |
| US-20140377184-A1 | Methods and Compositions Related to Targeting Tumors and Wounds | SANFORD BURNHAM MED RES INST (US) | 2014-12-25 | — | — | US | disclosed |
| US-8815804-B2 | Methods and compositions related to targeting tumors and wounds | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2014-08-26 | — | — | US | disclosed |
| EP-1986682-B1 | METHODS AND COMPOSITIONS RELATED TO TARGETING TUMORS AND WOUNDS | BURNHAM INST MEDICAL RESEARCH (US) | 2013-08-28 | — | — | EP | disclosed |
| EP-2510943-A1 | Methods and compositions related to targeting tumors and wounds | The Burnham Institute for Medical Research (US) | 2012-10-17 | — | — | EP | disclosed |
| US-20090214429-A1 | METHODS AND COMPOSITIONS RELATED TO TARGETING TUMORS AND WOUNDS | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-08-27 | — | — | US | disclosed |
| EP-1986682-A2 | METHODS AND COMPOSITIONS RELATED TO TARGETING TUMORS AND WOUNDS | The Burnham Institute for Medical Research (US) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007092447-A2 | METHODS AND COMPOSITIONS RELATED TO TARGETING TUMORS AND WOUNDS | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2007-08-16 | — | — | WO | disclosed |