Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 5/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10107240 | 1.00 | HCRTR2 (0.38) | HCRTR2HCRTR1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL429519 | 1.00 | HCRTR2 (0.38) | HCRTR2HCRTR1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL16433631 | 0.94 | HCRTR2 (0.36) | HCRTR2HCRTR1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL385424 | 0.86 | HCRTR2 (0.38) | HCRTR2HCRTR1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL384963 | 0.84 | SMN1; SMN2 (0.45) | HCRTR2HCRTR1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL383378 | 0.82 | HCRTR2 (0.39) | HCRTR2HCRTR1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL13799809 | 0.82 | HCRTR2 (0.39) | HCRTR2HCRTR1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL10107118 | 0.82 | HCRTR2 (0.39) | HCRTR2HCRTR1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL16433639 | 0.78 | SMN1; SMN2 (0.45) | HCRTR2HCRTR1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL16433610 | 0.76 | HCRTR2 (0.37) | HCRTR2HCRTR1SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE45364-E1 | Cyclic amine compound and pest control agent | NIPPON SODA CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |
| EP-1731518-B1 | CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO (JP) | 2014-06-25 | — | — | EP | disclosed |
| US-8101768-B2 | Cyclic amine compound and pest control agent | NIPPON SODA CO., LTD. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-7868178-B2 | Cyclic amine compound and pest control agent | NIPPON SODA CO., LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20090143443-A1 | CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2009-06-04 | — | — | US | disclosed |
| US-7485727-B2 | Cyclic amine compound and pest control agent | NIPPON SODA CO., LTD. (JP) | 2009-02-03 | — | — | US | disclosed |
| US-20080319003-A1 | CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2008-12-25 | — | — | US | disclosed |
| US-20080045569-A1 | Cyclic Amine Compound and Pest Control Agent | NIPPON SODA CO., LTD. (JP) | 2008-02-21 | — | — | US | disclosed |
| EP-1731518-A1 | CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2006-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045569-A1 | Cyclic Amine Compound and Pest Control Agent | H1-0, H1-2, H1-4 | HCRTR2 202/4885HCRTR1 41/4885SMN1; SMN2 2535/4885 |
| US-20090143443-A1 | CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | TAAR1, CBR3, CBR1 | HCRTR2 60/4885HCRTR1 13/4885SMN1; SMN2 2914/4885 |
| US-20080319003-A1 | CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | H1-0, H1-2, H1-4 | HCRTR2 260/4885HCRTR1 50/4885SMN1; SMN2 2482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.