Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.48 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4294005 | 1.00 | SPHK1 (0.48) | SPHK1HAO1EPHX1EPHX2S1PR1 | |
| SCHEMBL4296871 | 0.91 | S1PR1 (0.52) | SPHK1HAO1EPHX1EPHX2S1PR1 | |
| SCHEMBL4290752 | 0.91 | S1PR1 (0.52) | SPHK1HAO1EPHX1EPHX2S1PR1 | |
| SCHEMBL4291859 | 0.91 | S1PR1 (0.52) | SPHK1HAO1EPHX1EPHX2S1PR1 | |
| SCHEMBL4296068 | 0.90 | SPHK1 (0.43) | SPHK1HAO1EPHX1EPHX2S1PR1 | |
| SCHEMBL4297651 | 0.90 | SPHK1 (0.49) | SPHK1HAO1EPHX1EPHX2S1PR1 | |
| Hydrochloric Acid SCHEMBL4295936 | 0.89 | S1PR1 (0.51) | SPHK1HAO1EPHX1EPHX2S1PR1 | |
| SCHEMBL4296078 | 0.87 | RARB (0.53) | SPHK1HAO1EPHX1EPHX2S1PR1 | |
| SCHEMBL4291433 | 0.85 | S1PR1 (0.49) | SPHK1HAO1EPHX1EPHX2S1PR1 | |
| SCHEMBL4288503 | 0.85 | CNR1 (0.39) | SPHK1EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264469-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIO-PROJET (FR) | 2009-10-22 | — | — | US | claimed |
| US-20090264469-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIO-PROJET (FR) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264469-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES | S1PR2, S1PR1, S1PR5 | SPHK1 7/4885HAO1 2409/4885EPHX1 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.