SCHEMBL4296121

SCHEMBL4296121

COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)CCN)c(OCCCO)c(OC)c1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2733238 0.90 PIK3CG (0.69) PIK3CG
SCHEMBL15199250 0.89 PIK3CG (0.55) PIK3CG
SCHEMBL4285724 0.88 PIK3CG (0.66) PIK3CG
SCHEMBL4288292 0.86 PIK3CG (0.59) PIK3CG
SCHEMBL4287398 0.86 PIK3CG (0.53) PIK3CG
SCHEMBL4294735 0.85 PIK3CG (0.52) PIK3CG
SCHEMBL4294324 0.85 PIK3CG (0.54) PIK3CG
SCHEMBL4290119 0.85 PIK3CG (0.56) PIK3CG
SCHEMBL2721570 0.85 PIK3CG (0.60) PIK3CG
SCHEMBL2721959 0.84 PIK3CG (0.62) PIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012052102-A1 QUINOXALINE DERIVATES MERCK PATENT GMBH (DE) 2012-04-26 WO disclosed