Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL12472882 | 0.86 | TSHR (0.82) | TSHRALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL21829112 | 0.84 | TSHR (0.63) | TSHRALDH1A1GAAMAPK1TP53 | |
| Alcohol SCHEMBL28153354 | 0.82 | TSHR (0.82) | TSHRALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL27799665 | 0.82 | TSHR (1.00) | TSHRALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL15072 | 0.82 | — | — | |
| Acrylic Acid SCHEMBL29249578 | 0.81 | TSHR (0.72) | TSHRALDH1A1GAAMAPK1MEN1 | |
| Acrylic Acid SCHEMBL6888124 | 0.80 | TSHR (0.58) | TSHRALDH1A1GAAMAPK1TP53 | |
| Water SCHEMBL23706522 | 0.80 | — | — | |
| SCHEMBL9245718 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL22401379 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8323221-B2 | Tissue temperature indicating element for ultrasound therapy | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-12-04 | — | — | US | disclosed |
| US-20090264308-A1 | BIOSENSOR SOLID SUBSTRATE WITH INTEGRATED TEMPERATURE CONTROL AND A METHOD TO MAKE THE SAME | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2009-10-22 | — | — | US | disclosed |